Amazing results for a study of rectal cancer patients: all patients treated were cured

Amazing results for a study of rectal cancer patients. All 18 patients who took part in a clinical trial recovered from cancer after receiving the same treatment, writes The New York Times.

Although the study was conducted on a small number of patients, the specialists were impressed with the results, which brought “tears of happiness” for patients and their families. After treatment, the cancer was not detected by endoscopes, CT scans or MRIs.

Dr. Luis Diaz of the Memorial Sloan Kettering Cancer Center, author of the study published in the New England Journal of Medicine, which explains the results of the study, said it was the first known study in which treatment completely eliminated tumors. “I think this is the first time this has happened in the history of cancer,” said Dr. Diaz.

Dr. Alan P. Venook, a colorectal cancer specialist at the University of California, San Francisco, who disagreed with the study, agrees. A complete remission of each patient is something “unheard of,” he said.

In addition, none of the patients suffered significant complications from the treatment.

Dostarlimab was given every three weeks for six months and cost about $ 11,000 / dose. The treatment contains monoclonal antibodies that “unmask” cancer cells and allow the immune system to identify and destroy them.

However, experts point out that more studies are needed to clearly determine the effects of treatment.

The absence of significant side effects, said Dr. Venook, means “either they haven’t treated enough patients, or somehow these cancers are just different.”

In an editorial accompanying the paper, Dr. Hanna K. Sanoff of the University of North Carolina Lineberger Comprehensive Cancer Center, who was not involved in the study, called it “small but convincing.” She added, however, that it was unclear whether the patients were cured. “Little is known about how long it takes to find out if a complete clinical response to Dostarlimab is equivalent to a cure,” Dr. Sanoff told the editorial.

Dr. Kimmie Ng, a colorectal cancer expert at Harvard Medical School, said that while the results were “remarkable” and “unprecedented,” more tests were needed.

Publisher: AP

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